After years of not understsanding why I was having a hard time losing weight, a doctor of mine FINALLY figured out my thyroid is underactive (hypothyroidism). I think b/c I am young the doctors just didn't bother to test it. Anways, it causes weight gain and difficulty losing weight (as well as a lot of other symptoms, including depression). I have been on my med now for a month and can already tell a difference! Get it checked out!!!!